diff --git a/dev/devicelab/bin/tasks/module_test_ios.dart b/dev/devicelab/bin/tasks/module_test_ios.dart
index b01129e7a8..f82ff36559 100644
--- a/dev/devicelab/bin/tasks/module_test_ios.dart
+++ b/dev/devicelab/bin/tasks/module_test_ios.dart
@@ -250,6 +250,7 @@ Future<void> main() async {
             'CODE_SIGN_IDENTITY=-',
             'EXPANDED_CODE_SIGN_IDENTITY=-',
             'CONFIGURATION_BUILD_DIR=${tempDir.path}',
+            'COMPILER_INDEX_STORE_ENABLE=NO',
           ],
           environment: <String, String> {
             'FLUTTER_ANALYTICS_LOG_FILE': analyticsOutputFile.path,
@@ -294,6 +295,7 @@ Future<void> main() async {
             'CODE_SIGN_IDENTITY=-',
             'EXPANDED_CODE_SIGN_IDENTITY=-',
             'CONFIGURATION_BUILD_DIR=${tempDir.path}',
+            'COMPILER_INDEX_STORE_ENABLE=NO',
           ],
           canFail: true
         );
diff --git a/packages/flutter_tools/lib/src/macos/build_macos.dart b/packages/flutter_tools/lib/src/macos/build_macos.dart
index 0d5b086ac8..95fa007671 100644
--- a/packages/flutter_tools/lib/src/macos/build_macos.dart
+++ b/packages/flutter_tools/lib/src/macos/build_macos.dart
@@ -54,6 +54,7 @@ Future<void> buildMacOS({
     '-derivedDataPath', flutterBuildDir.absolute.path,
     'OBJROOT=${fs.path.join(flutterBuildDir.absolute.path, 'Build', 'Intermediates.noindex')}',
     'SYMROOT=${fs.path.join(flutterBuildDir.absolute.path, 'Build', 'Products')}',
+    'COMPILER_INDEX_STORE_ENABLE=NO',
   ]);
   final Status status = logger.startProgress(
     'Building macOS application...',
diff --git a/packages/flutter_tools/test/general.shard/commands/build_macos_test.dart b/packages/flutter_tools/test/general.shard/commands/build_macos_test.dart
index e9310ccf9c..fcf1819ab1 100644
--- a/packages/flutter_tools/test/general.shard/commands/build_macos_test.dart
+++ b/packages/flutter_tools/test/general.shard/commands/build_macos_test.dart
@@ -97,6 +97,7 @@ void main() {
       '-derivedDataPath', flutterBuildDir.absolute.path,
       'OBJROOT=${fs.path.join(flutterBuildDir.absolute.path, 'Build', 'Intermediates.noindex')}',
       'SYMROOT=${fs.path.join(flutterBuildDir.absolute.path, 'Build', 'Products')}',
+      'COMPILER_INDEX_STORE_ENABLE=NO',
     ])).thenAnswer((Invocation invocation) async {
       fs.file(fs.path.join('macos', 'Flutter', 'ephemeral', '.app_filename'))
         ..createSync(recursive: true)